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Abstract. . .  Hospital) has made a major contribution to the problem of sleep apnea induced hypertension . Professor Sullivan pioneered nasal CPAP as an effective treatment for sleep apnoea syndrome and has over 90 scientific publications in the area. Notably, in the field of hypertension research, the work of his team has been instrumental in showing the effectiveness of this treatment for reducing blood pressure in sleep apnea in patients (see Wilcock et al 1998). The Muscle Cell Function Laboratory , headed by Professor David . . .
. . .  measured using fluorescent methods and the distribution of ionic changes can be studied using confocal microscopy. Professor Allen developed the first method for measuring intracellular calcium in cardiac muscle using the luminescent protein aequorin. Current research involves studies on Pacemaker cells where the Laboratory is examining the mechanisms which control the firing rate of pacemaker cells and have discovered that the Na/Ca exchanger acts as a pacemaker current. Ionic regulation in the heart during ischaemia . . .
. . .  information about the state of calcium release sites and calcium stores in the heart. During acidosis and ischaemia, arrhythmias are more common and seem to be related to changes in calcium handling which can be studied by observing the frequency and magnitude of the calcium sparks (Balnave & Vaughan-Jones, 2000).  . . .
. . .  mRNA and showed how cyclic AMP modulates their effect on stability of this mRNA ( J Biol Chem 2003). Prof Morris has an extensive review coming out in a forthcoming issue of J Hypertens on the molecular basis of longevity. The David Read Laboratory at The University of Sydney, headed by Professor Colin Sullivan (also the director of the Australian Centre for Advanced Medical Technology on Obstructive Sleep Apnoea at Royal Prince Alfred Hospital) has made a major contribution to the problem of sleep apnea induced . . .
. . .  showed how cyclic AMP modulates their effect on stability of this mRNA ( J Biol Chem 2003). Prof Morris has an extensive review coming out in a forthcoming issue of J Hypertens on the molecular basis of longevity. The David Read Laboratory at The University of Sydney, headed by Professor Colin Sullivan (also the director of the Australian Centre for Advanced Medical Technology on Obstructive Sleep Apnoea at Royal Prince Alfred Hospital) has made a major contribution to the problem of sleep apnea induced hypertension . . .
--2765,5,276,2919,13825

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Hypertension Research at the University of Sydney

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