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Abstract: . . . as you evaluate the infant. -Chest radiograph Page 2 Persistent Pulmonary Hypertension 88 Copyright 2004 The Regents of the University . . . . . . respiratory distress or CO 2 retention. The aim is reduction of PVR through pulmonary vasodilator therapy, including the following as needed: -High inspired oxygen concentration. . . . . . . detect R ? L shunting at ductus arteriosus). A difference of =10% suggests marked pulmonary hypertension . -Cardiology consultation and echocardiogram to R/O congenital heart disease. . . . . . . pharmacologic paralysis, as needed. Minimize handling. - ECMO is needed for those in whom less invasive therapy is not effective in maintaining oxygenation, normal acid-base status or hemodynamic stability. . . . . . . dose of 5 mcg/kg per min IV and increase as necessary. Dobutamine is less effective in newborns and may lower blood pressure. - Adequate sedation , pharmacologic paralysis, as needed. . . . . . . Regents of the University of California Persistent Pulmonary Hypertension of the Newborn (PPHN) DEFINITION: PPHN is persistence after birth of the high pulmonary arterial pressure . . . --1202,6,100,1670,6010
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