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Abstract: . . . data. Thus, analyses of the trial results were not reported based on intent- to-treat. The GLT follow-up study 35 was also rated to be of poor quality for the same reason, although the primary trial 14,33 was rated fair. The OHTS and EMGT studies provide good evidence that treatment for ocular hypertension and early POAG is beneficial. 12,21 Because . . . . . . Laser Treatment (GLT) 33 study compared initial treatment with ALT to a stepwise regimen of topical and systemic ocular hypotensive medications. Patients were recruited at 8 tertiary care clinical centers. Thirty-two percent of participants had received glaucoma treatment prior to study entry. Forty-four percent of participants were black, and all participants had elevated IOP at baseline . . . . . . good evidence that treatment for ocular hypertension and early POAG is beneficial. 12,21 Because only a small percentage of people with ocular hypertension ever progress to POAG, screening and treatment for ocular hypertension is probably not warranted, particularly given the poor sensitivity and specificity of IOP measurements in detecting increased IOP. 7 If . . . . . . medical and surgical treatment result in similar visual field outcomes. In the CIGTS study, 38.1% of participants were black. In an analysis Page 21 18 controlling for treatment effect of age and gender, non-white race remained a significant predictor of progression (OR 1.50; 95% CI, 1.08-2.07). The GLT study compared initial treatment with ALT to a stepwise regimen . . . . . . gender, non-white race remained a significant predictor of progression (OR 1.50; 95% CI, 1.08-2.07). The GLT study compared initial treatment with ALT to a stepwise regimen of topical and systemic ocular hypotensive medications. 14,33 In the first 3.5 years median follow-up, approximately the same number of eyes showed . . . . . . and treatment for ocular hypertension is probably not warranted, particularly given the poor sensitivity and specificity of IOP measurements in detecting increased IOP. 7 If ocular hypertension is incidentally found as part of a routine eye examination, treatment may be warranted if IOP is substantially increased. 51 Also, we do not know whether the results of the . . . . . . effect of age and gender, non-white race remained a significant predictor of progression (OR 1.50; 95% CI, 1.08-2.07). The GLT study compared initial treatment with ALT to a stepwise regimen of topical and systemic ocular hypotensive medications. 14,33 In the first 3.5 years median follow-up, approximately the same number of eyes showed . . . --3000,7,214,3371,64652
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