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Abstract: . . . 1993; 328-30. Kinnard DR, Harris M, Hossack KF. Endurance testing for evaluation of antianginal therapy with amlodipine, a calcium channel blocking agent. J Am Col Cardiol 1988; 12:791-6. Jackson NC,Lee PS, Reynolds G,et al. Improvement of treadmill time to angina by amlodipine. Br J Clin Pharmacol 1985; 20:248P. 10. 11. Gottlieb SO , Weisfeldt ML, Ouyang P, et al. Effect of the addition of propranolol to therapy with nife- dipine for unstable angina pectoris : a randomised double blind ,placebo -controlled trial. Circulation . . . . . . angina . Am J Cardiol 1982; 49:125-32. Hill JA, Gonzalez JI, Kolb R, et al. Effects of atenolol alone, nifedipine alone and their combination on ambulant myocardial ischaemia.Am JCardiol1991; 67:671-5. ElTamimi H, Davies GJ.Optimal control ofmyocar- dial ischaemia: the benefit of a fixed combination of atenolol and nifedipine in patients with chronic stable angina . Br Heart J 1992; 68: 291-5. 117 July 1994 f HK Coll Cardiol, Vol 2 . . . . . . withdrawal in one patient. One limitation of this study was the absence of a placebo control group. A double blind placebo control trial may resolve this issue. J HK Coll Cardiol, Vol 2 July 1994 116 Page 5 AMLODIPINE IN THE TREATMENT OF STABLE ANGINA PECTORIS Conclusion In patients with chronic stable angina pectoris , amlodipine improves the subjective symptoms. The objectivesymptoms can be signifi- cantly improved when treated with amlodipine alone or in combination with . . . . . . atenolol alone, nifedipine alone and their combination on ambulant myocardial ischaemia.Am JCardiol1991; 67:671-5. ElTamimi H, Davies GJ.Optimal control ofmyocar- dial ischaemia: the benefit of a fixed combination of atenolol and nifedipine in patients with chronic stable angina . Br Heart J 1992; 68: 291-5. 117 July 1994 f HK Coll Cardiol, Vol 2 . . . . . . alone, nifedipine alone and their combination on ambulant myocardial ischaemia.Am JCardiol1991; 67:671-5. ElTamimi H, Davies GJ.Optimal control ofmyocar- dial ischaemia: the benefit of a fixed combination of atenolol and nifedipine in patients with chronic stable angina . Br Heart J 1992; 68: 291-5. 117 July 1994 f HK Coll Cardiol, Vol 2 . . . --3000,5,300,2886,17376
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