Abstract: . . .  alternative. However, the high- dose combination therapy appears to produce a greater inci- dence of adverse events, so a lower-dose combination therapy (nifedipine 20 mg and talinolol 100 mg) may provide an ac- ceptable compromise between efficacy and tolerability in cer- tain patients. Acknowledgements This study was supported by a grant from ASTA Medica AG, Germany. References 1. Management of stable angina pectoris . Recommendations of . . .
. . .  exer- cise after nifedipine consumption may be a useful indicator of those patients who are likely to gain the most advantage from nifedipine anti-anginal therapy. Overall, this study suggests that monotherapy with either the slow-release formulation of nifedipine or with talinolol provides anti-anginal and anti-ischaemic effects in patients with stable angina pectoris . This study also suggests greater efficacy with combination therapy. Therefore, in those . . .
. . .  coronary constriction in the develop- Page 7 J Clin Basic Cardiol 2000; 3: 34 The NITAAP Study ORIGINAL PAPERS, CLINICAL ment of effort angina in some patients. The anti-anginal ef- fect of nifedipine, therefore, may be at its greatest in this par- ticular group of patients. Thus, in the clinical setting, an in- crease of double product of more than 14 units at peak exer- cise after nifedipine consumption may be a useful indicator . . .
. . .  of nifedipine 40 mg and talinolol 200 mg) is a viable alternative. However, the high- dose combination therapy appears to produce a greater inci- dence of adverse events, so a lower-dose combination therapy (nifedipine 20 mg and talinolol 100 mg) may provide an ac- ceptable compromise between efficacy and tolerability in cer- tain patients. Acknowledgements This study was supported by a grant from ASTA Medica AG, Germany. References  . . .
. . .  namic exercise. Circulation 1974; 50: 117989. 12. Pepine CJ. New insights in measurement of myocardial ischaemia. Am J Cardiol 1992; 70: 19G24G. 13. Pfisterer M, Glaus L, Burkat F. Comparative effects of nitroglycerin, nifedipine and metoprolol on regional left ventricular function in patients with one ves- sel coronary disease. Circulation 1983; 67: 291301.  . . .
. . .  medications (particularly the high-dose combination of nifedipine 40 mg and talinolol 200 mg) is a viable alternative. However, the high- dose combination therapy appears to produce a greater inci- dence of adverse events, so a lower-dose combination therapy (nifedipine 20 mg and talinolol 100 mg) may provide an ac- ceptable compromise between efficacy and tolerability in cer- tain patients. Acknowledgements This study was supported by a grant from ASTA . . .
--3000,6,250,3353,32807