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Abstract: . . . future IHD events Thrombosis Prevention Trial -1983-92, Great Britain -low-dose antithrombotic treatment in preventing angina and major CHD -Prevention of CHD- results published in 1998 . . . . . . practices in Great Britain Demographics not reported, but most likely Caucasian High risk patients Is the treatment feasible? Requires monitoring of INR at least once every 6 months Study was conducted in a controlled environment . . . . . . of angina lowered by warfarin? More evidence needed 2. Low dose warfarin prevents CHD in high risk patients- must weigh risks and benefits. 3. ASA increases incidence of angina significantly . . . . . . 7 Hemorrhagic stroke 4 8 9 12 Other major bleed (GI + others) P (n=1272) A (n=1268) W (n=1268) WA (n=1277) . . . . . . evidence needed 2. Low dose warfarin prevents CHD in high risk patients- must weigh risks and benefits. 3. ASA increases incidence of angina significantly . . . . . . needed 2. Low dose warfarin prevents CHD in high risk patients- must weigh risks and benefits. 3. ASA increases incidence of angina significantly . . . --1555,6,130,1785,7774
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