Abstract: . . .  Sidki K, al-Marshedy AR, Judzewitsch R: Addison's disease, hypertension, renal and hepatic microthrombosis in 'pri- mary' antiphospholipid syndrome. Postgrad Med J 1991, 67: 385-388. 7. Teyssier G, Gautheron V, Absi L, Galambrun C, Ravni C, Lepetit JC: [Anticardiolipin antibodies, cerebral ischemia and adrenal hemorrhage in a newborn infant]. Arch Pediatr 1995, 2: 1086-1088. 8. Nochy D, Daugas E, Droz D, Beaufils H, Grunfeld JP, Piette JC, Bariety J, Hill G: The intrarenal vascular lesions associated with pri- mary antiphospholipid syndrome. J Am Soc Nephrol 1999, 10: 507-518. 9. Pelkonen P, Simell O, Rasi V, Vaarala O: Venous thrombosis asso- ciated with lupus anticoagulant and anticardiolipin antibodies. Acta Paedatr Scand 1998, 77: 767-772. 10. Rose C, Goldsmith DP: Childhood adrenal insufficiency, chorea, and antiphospholipid antibodies. Ann Rheum Dis 1990, 49: 421-422. 11. Espinosa G, Santos E, Cervera R, Piette JC, de la Red G, Gil V, Font J, Couch R, Ingelmo M, Asherson RA: Adrenal involvement in the antiphospholipid syndrome. Clinical and immunological characteristics of 86 patients. Medicine 2003, 82: 106-116. Additional File 1 Table 2 Click here for file [http://www.biomedcentral.com/content/supplementary/1477- 9560-3-6-S1.doc]  . . .
. . .  with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp Bio Med central Thrombosis Journal 2005, 3 :6 http://www.thrombosisjournal.com/content/3/1/6 Page 4 of 4 (page number not for citation purposes) In a recent study Nochy et al. reported 16 patients with APS. All of them had biopsy proven vascular nephropathy caused by small vessel vaso-occlusive lesions [ 8 ]. There- fore, it is possible that involvement of the small renal ves- sels also played a role in our patient. This case demonstrates that APS in childhood may present with a diverse and severe set of symptoms. Adrenal hem- orrhage due to thrombosis should be considered as a manifestation of the antiphospholipid syndrome. These patients must be closely monitored because consecutive thrombosis with secondary hemorrhage may rapidly . . .
--3000,2,750,3163,20359