Abstract: . . .  human endothelial cells, further supporting CRP association and atherothrombosis. 19 The present report is the first to show that CRP is a risk factor and possible causal agent, rather than merely a risk marker, for increased rate of arterial thrombosis in vivo and worsened outcome after controlled vascular injury. These findings might help us understand the recent observation that, whereas lipoproteins predict burden of atherosclerotic dis-  . . .
. . .  increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation . 2003;107:397403. Danenberg et al Arterial Thrombosis in CRPtg Mice 515  . . .
. . .  rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils. Arte- rioscler Thromb Vasc Biol . 2000;20:335342. 13. Reis ED, Roque M, Dansky H, et al. Sulindac inhibits neointimal for- mation after arterial injury in wildtype and apolipoprotein Edeficient mice. Proc Natl Acad Sci U S A . 2000;97:1276412769. 14. Folsom A, Pankow J, Tracy R, et al. Association of C-reactive protein with markers of prevalent atherosclerotic disease. . . .
. . .  protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation . 2003;107:397403. Danenberg et al Arterial Thrombosis in CRPtg Mice 515  . . .
. . .  accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils. Arte- rioscler Thromb Vasc Biol . 2000;20:335342. 13. Reis ED, Roque M, Dansky H, et al. Sulindac inhibits neointimal for- mation after arterial injury in wildtype and apolipoprotein Edeficient mice. Proc Natl Acad Sci U S A . 2000;97:1276412769. 14. Folsom A, Pankow J, Tracy R, et al. Association of C-reactive protein with markers of prevalent atherosclerotic disease. Am J Cardiol . . .
. . .  link between vascular inflammation and clotting activation. Arterioscler Thromb Vasc Biol . 2002;22:782787. 19. Devaraj S, Xu DY, Jialal I. C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation . 2003;107:397403. Danenberg et al Arterial Thrombosis in CRPtg Mice 515  . . .
--3000,6,250,3015,20502