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Abstract: . . . patients with other malignancies (1,6). MM, in the absence of hyperviscosity, is not associated with a particularly high risk for thromboembolism (1). The results in different studies indicate that when combinations of chemotherapy and thalidomide are used, effective prophylactic anticoagulation should be implemented in all, at least during the first few cycles of treatment (2,3,4,6,9). For the known contribution of increased platelet activity in malignancy, antiplatelet therapy as an additional or alternative strategy to warfarin should be tested during thalidomide therapy (6). 249 Vol: 36 No: 4 Arterial Thrombosis in Refractory Multiple Myeloma August 2006 . . . . . . four patients treated with thalidomide. Leuk Lymphoma 2005; 46: 239-242. 7. Bennet C, Schumock G, Desai A, Kwaan H, Raisch D, Newlin R. Thalidomide-associated deep vein thrombosis and pulmonary embolism. Am J Med 2002; 113: 603-606. 8. Bowcock SJ, Rassam SMV, Ward SM, Turner JT, Laffan M. Thromboembolism in patients on thalidomide for myeloma. Hematology 2002; 7: 51-53. 9. Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal AV et al. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001; 98: 1614-1615. . . . . . . Thalidomide-associated deep vein thrombosis and pulmonary embolism. Am J Med 2002; 113: 603-606. 8. Bowcock SJ, Rassam SMV, Ward SM, Turner JT, Laffan M. Thromboembolism in patients on thalidomide for myeloma. Hematology 2002; 7: 51-53. 9. Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal AV et al. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001; 98: 1614-1615. . . . . . . Thalidomide-associated deep vein thrombosis and pulmonary embolism. Am J Med 2002; 113: 603-606. 8. Bowcock SJ, Rassam SMV, Ward SM, Turner JT, Laffan M. Thromboembolism in patients on thalidomide for myeloma. Hematology 2002; 7: 51-53. 9. Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal AV et al. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001; 98: 1614-1615. . . . --3000,4,375,2710,15854
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