Abstract: . . .  diagnostic test, is the most sensitive and specific method for diagnosis of DVT, but exposes patients to the risks associated with contrast material. 16- 8 CARDIAC AND VASCULAR DISORDERS Table 16-5 Optimal Therapeutic Range and Duration of Warfarin Therapy (continued) Valve replacement (mechanical) Aortic Bileaflet (or Medtronic Hall tilting disk) In NSR, normal EF, normal LA size 2.5 (2.03.0) chronic All others 3.0 (2.53.5) chronic Or 2.03.0 plus aspirin 81 mg a Tilting disk (all other brands) 3.0 (2.53.5) chronic Or 2.03.0 plus aspirin 81 mg a Ball and cage 3.0 (2.53.5) . . .
. . .  dose should be simplified to 20,000 U SC every 12 hours. L.N.s aPTT should be checked 6 hours after the first dose, with adjustment of dosing as necessary. Because of the reduced bioavailability of SC heparin in comparison with IV administration, increased dosing may be required. A weight-based dosing nomogram, specific for a reagent with a THROMBOSIS 16- 11 Koda-Kimble_Ch16_001-034 4/6/04 8:42 AM Page 11 Page 12 therapeutic aPTT range of 60 to 100 seconds, is described in Table 16-7. REVERSAL OF EFFECT 14. P.B. is a 64-year-old woman with DVT. On day 4 of hep- arin therapy, she received 25,000 U of heparin . . .
. . .  therapeutic aPTT range of 60 to 100 seconds, is described in Table 16-7. REVERSAL OF EFFECT 14. P.B. is a 64-year-old woman with DVT. On day 4 of hep- arin therapy, she received 25,000 U of heparin during a 1-hour period as a result of an infusion pump malfunction. The infusion was stopped and within 30 minutes, she became diaphoretic and hypotensive. Bright red blood was evident upon rectal examina-  . . .
. . .  disk 3.0 (2.53.5) chronic Or 2.03.0 plus aspirin 81 mg a Ball and cage/caged disk 3.0 (2.53.5) chronic With aspirin 81 mg QD With additional risk factors or post-TE 3.0 (2.53.5) chronic Add aspirin 81 mg QD a In patients with risks for hemorrhage. ASA, acetylsalicylic acid; AT, antithrombin; CAD, coronary artery disease; EF, ejection fraction; HF, heart failure; HTN, hypertension; LA, left atrial; LV, left ventricular; NSR, normal sinus rhythm; TE, thromboembolism; TIA, transient ischemic attack. Koda-Kimble_Ch16_001-034 4/6/04 8:42 AM Page 8 Page 9 Treatment Baseline Information  . . .
--3000,4,375,3009,64553