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Abstract: . . . associated behavioural patterns. Having established CBT as a beneficial treatment approach, subsequent studies have sought to identify the active components of the CBT package. In this regard, graded physical exercise therapy has been found in several studies to be significantly better than comparators such as relaxation therapy, notably in reducing symptom severity and gaining improved function. 6-8 In particular, Fulcher and MJA Vol 180 3 May 2004 437 . . . . . . thromboembolism. Blood 1995; 86: 3685-3691. 5. Galli M, Luciani D, Bertolini G, Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid antibody syndrome: a systematic review of the literature. Blood 2003; 101: 1827-1832. 6. Schulman S, Svenungsson E, Granqvist S, et al. Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Am J Med 1998; 104: 332-338. 7. Health Insurance Commission. Medicare Benefits Schedule (MBS) item statistics reports. MBS statistics 20022003. Available at: www.hic.gov.au/statistics/ dyn_mbs/forms/mbs_tab4.shtml (accessed Feb 2004). 8. Khamashta MA, Cuadrado MJ, Loizou S, et al. The management of thrombosis in the antiphospholipid antibody syndrome. N Engl J Med 1995; 332: 993-997. . . . . . . Antiphospholipid thrombosis : clinical course after the first thrombotic event in 70 patients. Ann Intern Med 1992; 117: 303-308. 10. Palareti G, Leali N, Coccheri S, et al. Bleeding complications of oral anticoagu- lant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Lancet 1996; 348: 423-428. 11. Crowther MA, Ginsberg JS, Julian J, et al. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphos- pholipid antibody syndrome. N Engl J Med 2003; 349: 1133-1138. ? Graded physical exercise is no panacea, but is beneficial M UCH REMAINS UNKNOWN ABOUT the enigmatic clinical disorder chronic fatigue syndrome (CFS). Apart from clear evidence implicating certain infections as a trigger, and reproducible evidence of increased rates of comorbid depression, the aetiology . . . --2880,3,480,2710,14401
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