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Abstract: . . . a classmate the different signs and symptoms. 3 Arteriosclerosis n Chronic disease of the arterial system n Characterized by an abnormal thickening and hardening of the vessel walls. Smooth muscle cells and collagen fibers move into the tunica intima causing stiffening Inhibits the arterys ability to change lumen size n Structural changes may be due to the normal aging process Changes in lipid, cholesterol, and phospholipids are contributing factors Page 2 4 Atherosclerosis Plaque Formation n A form of arteriosclerosis in which the hardening of the vessel walls are caused by soft deposits of intrarterial fat and fibrin that harden over time n Damaged endothelium n Fatty streak formation n . . . . . . Jugular vein distention 30 References n American Heart Association. 2002 Heart and Stroke Statistical Update. Dallas, Tex.: American Heart Association; 2001. n Bullock, B. A. & Reet, L. H. (2000). Focus on Pathophysiology. Philadelphia: Lippincott. n Corwin, E.J.(2000).Handbook of pathophysiology. Baltimore: Lippincott. n Hansen, M. (1998). Pathophysiology: Foundations of disease and clinical intervention. Philadelphia: Saunders. n Hartshorn, J. C., Sole, M. L., & Lamborn, M. L. (1997).Introduction to critical care nursing.Philadelphia: Saunders. n Huether, S. E., & McCance, K. L. (2002). Pathophysiology. St. Louis: Mosby. n http://www.heartsite.com n Illustrations in this presentation used are from HeartSite.com . . . . . . vessel walls. Smooth muscle cells and collagen fibers move into the tunica intima causing stiffening Inhibits the arterys ability to change lumen size n Structural changes may be due to the normal aging process Changes in lipid, cholesterol, and phospholipids are contributing factors Page 2 4 Atherosclerosis Plaque Formation n A form of arteriosclerosis in which the hardening of the vessel walls are caused by soft deposits of intrarterial fat and fibrin that harden over time n Damaged endothelium n Fatty streak formation n Fibrous plaque develops n Complicated lesion 5 Atherosclerosis (fat scar or atheromas) n Plaque can ulcerate or rupture before occluding the vessel n . . . --3000,3,500,3155,16077
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