Abstract: . . .  Alejandro Aquino, Leah Nchama, Heather Webb, Luigi Di Stefano, Ling-Chih Liang, Amy Lei, Kristina Rene, Vinod Rao, Bradley Miller, Elizabeth Harrison, Daniel Ma, Kyle Eash, Calvin Hu, Vincent Wong Page 13 CRP As a Screening Test: Introduction Statement of Question Discuss role of CRP as a potential risk marker for atherosclerotic disease, and its potential benefits for disease management. Arteriosclerosis is associated with inappropriate inflammation CRP is a marker of inflammation. CRP is one of the most well-studied non-traditional risk factors Does CRP provide additional information about a persons risk? When and how can these facts be used? Primary Prevention Secondary Prevention Treatment Page 14 CRP As a Screening Test: Background Information Atherosclerosis Traditional Risk . . .
. . .  As a Screening Test: Background Information Atherosclerosis: Epidemiology Men>Women, Diet, Race Diabetes increases risk WHO data 16.6 million deaths/year from cardiovascular disease 7.2 million die of heart disease, 5.5 million from stroke By 2020 estimate 25 million CVD deaths worldwide U.S. rate per 100,000 Men CVD death = 348, Women CVD death = 177 Page 16 CRP As a Screening Test: Background Information Inflammation Pathophysiology Stages Response to Injury Hypothesis Sources of immune response LDL Homocysteine Hypertension Infection Page 17 CRP As a Screening Test: Existing Studies Primary Prevention Studies Multiple Risk Factor Intervention Trial (MRFIT) Physicians Health Study Monitoring Trends and Determinants in . . .
. . .  Screening Test: Background Information Atherosclerosis: Epidemiology Men>Women, Diet, Race Diabetes increases risk WHO data 16.6 million deaths/year from cardiovascular disease 7.2 million die of heart disease, 5.5 million from stroke By 2020 estimate 25 million CVD deaths worldwide U.S. rate per 100,000 Men CVD death = 348, Women CVD death = 177 Page 16 CRP As a Screening Test: Background Information Inflammation Pathophysiology Stages Response to Injury Hypothesis Sources of immune response LDL Homocysteine Hypertension Infection Page 17 CRP As a Screening Test: Existing Studies Primary Prevention Studies Multiple Risk Factor Intervention Trial (MRFIT) Physicians Health Study Monitoring Trends and Determinants in Cardiovascular . . .
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