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Abstract: . . . JD: Effect of acute coronary occlusion on the size of the dinamically perfused coronary capillary bed in the dog. Microvasc Res 56: 95-103, 1998. 47. Cziraki A, Parkerson BJ, Fisher E and Catravas JD: Inhibition of pulmonary endothelial angiotensin converting enzyme activity by trandolaprilat in vivo . Drug Res 41: 22-23, 1998. 48. Iwai N, Shimoike H and Kinoshita M: Cardiac rennin - angiotensin system in the hypertrophied heart. Circulation 92: 2690-2696, . . . . . . and Mills L: Early effects of ionizing radiation on pulmonary endothelial angiotensin- converting enzyme and 5'-nucleotidase, in vivo . Toxicol Appl Pharmacol 94: 342-355, 1988. 31. Gillis NC: Measurement of endothelial metabolic functions in vivo . Ann Biomed Eng 15: 183-188, 1987. 32. Hammond GL, Cronau LH, Whittaker D and Gillis NC: Fate of prostaglandins E 1 and A 1 in the human pulmonary circulation. Surgery 81: 716-722, . . . . . . ectoenzyme function provide new means for the evaluation of pulmonary microvascular function in vivo . During the last 10 years, methodological advances have made possible the routine monitoring of ectoenzyme functions in vivo . Studies from this and other laboratories suggest that endothelial ectoenzyme functions can serve as markers for microvascular surface area as well as early indicators of endothelial cell injury and repair. The association between alterations . . . . . . Catravas JD: Effect of acute coronary occlusion on the size of the dinamically perfused coronary capillary bed in the dog. Microvasc Res 56: 95-103, 1998. 47. Cziraki A, Parkerson BJ, Fisher E and Catravas JD: Inhibition of pulmonary endothelial angiotensin converting enzyme activity by trandolaprilat in vivo . Drug Res 41: 22-23, 1998. 48. Iwai N, Shimoike H and Kinoshita M: Cardiac rennin - angiotensin system in the hypertrophied heart. Circulation 92: . . . . . . Bodin L, Korinek AM and Viars P: Inhaled nitric oxide in acute respiratory failure: dose-response curves. Intensive Care Med 20: 319-327, 1994. 23. Tomashefski JF Jr, Davies P, Boggis C, Greene R, Zapol WM and Reid LM: The pulmonary vascular lesions of the adult respiratory distress syndrome. Am J Pathol 112: 112-126, 1983. 24. Montgomery AB, Stager MA, Carrico J and Hudson LD: Cause of mortality in patients with the adult respiratory distress syndrome. . . . . . . interpretation of experimental results. The challenge for the next years will be 2-fold: i) to test this knowledge further in clinical practice in order to find out whether it can be useful routinely in the early diagnosis of lung disease , and ii) to exploit these experiences in gaining new insights into the physiology of the pulmonary circulation. Acknowledgments We would like to express our gratitude to John D. Catravas the director and regent professor . . . --3000,6,250,3461,55655
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