Abstract: . . .  Imaging of 3301 Elderly People. The Cardiovascular Health Study. Stroke . 1996; 27 (8): 1274- 82. 23. Skoog I, Nilsson L, Palmertz B, Andreasson LA, and Svanborg A. A population-based study of dementia in 85-year-olds. N Engl J Med . 1993; 328(3): 153-8. 24. Chui H. Rethinking Vascular Dementia: Moving from Myth to Mechanism. In: The Dementias. Growden JH and Rossor MN (eds). Butterworth-Heinemann, 1998. Table 4. Management (modified from reference #24) Risk factor modification (Primary prevention) Hypertension Hyperlipidemia Atrial fibrillation Smoking Treatment of underlying mechanism (Secondary prevention) Ischemia Acute: atherosclerosis, cardioembolism, . . .
. . .  amyloid angiopathy: sporadic, hereditary Treatment of established symptoms (Tertiary amelioration) Cognitive: amnesia, aphasia, neglect Behavioral: disinhibition, aggression Psychiatric: depression, anxiety, apathy Neurological: weakness, visual disturbance CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy AVM: arteriovenous malformation  . . .
. . .  Management (modified from reference #24) Risk factor modification (Primary prevention) Hypertension Hyperlipidemia Atrial fibrillation Smoking Treatment of underlying mechanism (Secondary prevention) Ischemia Acute: atherosclerosis, cardioembolism, vasculitis Chronic: atherosclerosis, CADASIL Hemorrhage Hypertension Vascular malformation: AVM, aneurysm Cerebral amyloid angiopathy: sporadic, hereditary Treatment of established symptoms (Tertiary amelioration) Cognitive: amnesia, aphasia, neglect Behavioral: disinhibition, aggression Psychiatric: depression, anxiety, apathy Neurological: weakness, visual disturbance CADASIL: cerebral autosomal dominant . . .
. . .  Neuropsychological and Electrophysiological Findings in Four Anatomical Groups Defined by Computerized Tomography. Brain . 1985: 108; 485-516. 19. Englund E. Neuropathology of White Matter Changes in Alzheimers Disease and Vascular Dementia. Dement Geriatr Cogn Disord . 1998; 9 (Suppl l): 6-12. 20. Roman GC. New Insight Into Binswanger Disease . Arch Neurol . 1999: 56 (9); 1061-1062. 21. Munoz D, Hastak S, Harper B, et al. Pathologic Correlates of Increased Signals of the Centrum Ovale on Magnetic Resonance Imaging. Arch Neuro . 50; 1993; 492-7. 22. Longstreth W, Manolio T, Arnold A, et al. Clinical Correlates of White Matter Findings on Cranial Magnetic Resonance Imaging . . .
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