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Abstract: . . . deterioration scale for scaling Alzheimers dis- ease. Am J Psychiatry 1988; 149 :16. 39 Wragg RE, Jeste DV. Neuroleptics and alternatives: management of behavioral symptoms and psychosis in Alzheimers disease and related conditions. Psychiatr Clin North Am 1988; 11 :185213. 40 Kitagaki H, Mori E, Hirono N, et al . Alteration of white matter MR signal intensity in fronto temporal dementia. . . . . . . for scaling Alzheimers dis- ease. Am J Psychiatry 1988; 149 :16. 39 Wragg RE, Jeste DV. Neuroleptics and alternatives: management of behavioral symptoms and psychosis in Alzheimers disease and related conditions. Psychiatr Clin North Am 1988; 11 :185213. 40 Kitagaki H, Mori E, Hirono N, et al . Alteration of white matter MR signal intensity in fronto temporal dementia. AJNR Am . . . . . . based upon the overall subject sample. 1.50 1.50 Standard score 0.00 0.50 1.00 1.00 0.50 Diagnostic group NoMild WMD Alzheimer's disease Ischaemic vascular dementia ModerateSevere WMD 45 Hargrave, Geck, Reed, et al on 17 February 2006 jnnp.bmjjournals.com Downloaded from . . . . . . of Department of Health and Human Services Task Force on Alzheimers disease . Neurology 1984; 34 :93943. 21 Chui HC, VictoroV JI, Margolin D, et al . Criteria of the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimers disease diagnostic and treatment centers. Neurology 1992; 42 :47380. 22 Gupta SR, Naheedy MH, Young JC, et al . Periventricular . . . . . . deterioration scale for scaling Alzheimers dis- ease. Am J Psychiatry 1988; 149 :16. 39 Wragg RE, Jeste DV. Neuroleptics and alternatives: management of behavioral symptoms and psychosis in Alzheimers disease and related conditions. Psychiatr Clin North Am 1988; 11 :185213. 40 Kitagaki H, Mori E, Hirono N, et al . Alteration of white matter MR signal intensity in fronto temporal dementia. . . . . . . doi:10.1136/jnnp.68.1.41 2000;68;41-46 J. Neurol. Neurosurg. Psychiatry Rita Hargrave, Laurie C Geck, Bruce Reed and Dan Mungas disease and ischaemic vascular disease Affective behavioural disturbances in Alzheimer's http://jnnp.bmjjournals.com/cgi/content/full/68/1/41 Updated information and services can be found at: These include: References . . . . . . 37 38 Future research is needed to validate our results and examine the contribution of additional demographic and neurobiological factors to the pathophysiology of aVective states/behavioural disturbances in dementia. Future research could consider issues such as (1) the relation between infarct location and Figure 3 Means and standard errors of means on the decreased . . . --3000,7,214,3519,44534
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