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Abstract: . . . community-dwelling volunteers. Psychol Med 2000b; 30:10171023 50. Fava M, Abraham M, Pava J, et al: Cardiovascular risk factors in depression: the role of anxiety and anger. Psychosomatics 1996; 37:3137 51. Paterniti S, Verdier-Taillefer M, Geneste C, et al: Low blood pres- sure and risk of depression in the elderly: a prospective, com- munity-based study. Br J Psychiatry 2000; 176:464467 52. Dierker L, Avenevoli S, Stolar M, et al: Smoking and depression: an examination . . . . . . AS, Traykov L, Caputo L, et al: Association of the apoli- poprotein-E epsilon-4 allele with late-onset depression. Neuroe- pidemiology 2001; 20:4:268272 17. Schmand B, Hooijer C, Jonker C, et al: Apolipoprotein-E pheno- type is not related to late-life depression in a population-based sample. Soc Psychiatry Psychiatr Epidemiol 1998; 33:2126 18. Holmes C, Russ C, Kirov G, et al: Apolipoprotein-E: depressive illness, depressive symptoms, and Alzheimers disease . Biol . . . . . . et al: Does depression predict cog- nitive function 9 to 12 years earlier?: evidence from a longitudinal study of elderly, community-dwelling volunteers. Psychol Med 2000b; 30:10171023 50. Fava M, Abraham M, Pava J, et al: Cardiovascular risk factors in depression: the role of anxiety and anger. Psychosomatics 1996; 37:3137 51. Paterniti S, Verdier-Taillefer M, Geneste C, et al: Low blood pres- sure and risk of depression in the elderly: a prospective, com- . . . . . . 45. Krishnan KR, Hays JC, Blazer D: MRI-defined vasculardepression. Am J Psychiatry 1997; 154:497501 46. Pauls J, Bandelow B, Ruther E, et al: Polymorphism of the gene Page 9 Genes in Vascular Disease and Depression 210 Am J Geriatr Psychiatry 12:2, March-April 2004 of angiotensin-converting enzyme: lack of association with mood disorder. J Neural Trans 2000; 107:13611366 47. Segman RH, Shapira Y, Modai I, . . . . . . 202 Am J Geriatr Psychiatry 12:2, March-April 2004 Genes Related to Vascular Disease (APOE, VLDL-R, DCP-1) and Other Vascular Factors in Late-Life Depression Jorge Cervilla, MRCPsych, M.D., Martin Prince, MRCPsych, M.D. Suzanne Joels, MRCPsych, Carsten Russ, Ph.D. Simon Lovestone, MRCPsych, . . . . . . postulated a familial common etiology for smoking and depression. 7,53 Our results suggest that, should a familial etiology exist for smoking and/or depression, this is unlikely to be mediated by loci such as APOE, VLDL-R, and/or DCP-1, at least at the polymorphisms studied. Similarly, our findings ex- clude the influence of vascular disease in the associ- ation between smoking and depression, adding sup- port to theories explaining the association . . . --3000,6,250,3332,44392
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